Cannabinoids, also known as endocannabinoids, are natural chemicals that regulate a wide range of physiological functions. They help us maintain our basic functions and fight illness. In the human body, these chemicals are produced by the endocannabinoid system and increase during illness. Tumor cells, in particular, express greater amounts of cannabinoid receptors than healthy cells. These differences suggest that the body’s natural levels of these compounds are higher in patients suffering from various disorders.
Cannabinoids
Natural cannabinoids, such as cannabichromene cbc, are made by the body and control brain activity. They are similar to monoamine neurotransmitters that activate receptors on nearby cells. These molecules have unique properties, acting on neurons through retrograde signaling. Because they are lipophilic molecules, they are not soluble in water and are part of the cell membranes. Unlike hormones, however, they act locally on target cells. Some studies have suggested that they influence the neuronal network of the brain.
Research shows that cannabinoids may have a role in reducing the effects of anxiety and stress. These compounds reduce the production of adrenal hormones and have a calming effect, which is useful for people suffering from anxiety disorders. In addition, cannabinoids are effective in reducing the onset of panic attacks.
Cannabinoid receptors
Cannabinoids act on human brain cells by activating cannabinoid receptors. These receptors are found in both the brain and other tissues. They regulate various functions, including appetite, pain, inflammation, mood, and sleep. The human body produces cannabinoids naturally, and they can also be found in cannabis plants.
The endocannabinoid system evolved over 500 million years ago and is wired into all vertebrates and invertebrates. This system aims to maintain homeostasis, or balance, in the body. Scientists have discovered that cannabinoid receptors are present in nearly every cell in the body. These receptors interact with the natural cannabinoids found in cannabis.
Studies on human cannabinoid receptors have indicated that the molecules inhibit pain and inflammation in humans.
Terpenes
Cannabis contains hundreds of different terpenes. However, only a handful of these compounds are of interest. These compounds are highly branched fatty acids with varying molecular functions.
One of the most important terpenes in cannabis is pinene. Found in pine trees and conifers, this terpene is responsible for the characteristic piney smell of some strains of cannabis. In addition, it has been found to have anti-inflammatory properties in cultured human cells. It may also help to improve airflow in the lungs.
Terpenes are also highly aromatic compounds responsible for the distinct smell of different varieties of cannabis. In addition, these compounds support other cannabis compounds by imparting flavors to the bud. It is known as the “ensemble effect,” in which one plant compound enhances the effect of the others.
CBD
CBD and cannabidiol have many uses in the body. Both are prescription drugs used to treat epilepsy, anxiety, pain, and other conditions. They are also being investigated for a variety of other purposes. However, despite promising research and potential uses, the FDA has not approved it for dietary use or clinical trials.
These compounds also have antiviral properties. They have been found to inhibit viral infection and reverse viral induction of genes related to chromatin modification and transcription. They also reverse the viral inhibition of ribosomes and neutrophils. CBD is also known to induce host stress responses. However, further research is needed to determine how CBD works as an antiviral.
Studies have shown that cannabinoids such as THC and CBD can affect the immune system and pain perception. These substances are extracted from several cannabis plants, including marijuana and industrial hemp. CBD and THC may have adverse effects, so it is important to consult a physician before taking them.
THC
Cannabinoids are compounds in cannabis that cause a range of physiological effects. THC is one of these compounds responsible for the euphoric and intoxicating effects that many people associate with marijuana. Inhaled cannabis contains roughly 50 percent THC. The lungs absorb this amount, rapidly absorbed into the bloodstream and brain. As a result, effects are evident within minutes. By contrast, oral cannabis contains less THC and is metabolized mainly by the liver. As a result, it delays the onset of effects and prolongs the duration of the effects. There is a great deal of research into the effects of cannabinoids individually and in combination.
